VSR_VIES

This repository contains the decision-analytic model files, and analytic outputs supporting a cost-effectiveness analysis of maternal respiratory syncytial virus (RSV) vaccination in Brazil under three scenarios: an aggregate administrative-data scenario, a scenario based on an external clinical-trial incidence benchmark (MATISSE), and a higher-capture scenario derived from linked hospitalization and birth records. The repository includes: (1) Amua decision-tree model files (.amua) for each scenario, including deterministic and probabilistic sensitivity analysis specifications; (2) raw and summarized outputs from one-way deterministic sensitivity analysis (DSA) and probabilistic sensitivity analysis (PSA, 10,000 Monte Carlo iterations) for each scenario. Individual-level linked microdata are not included, as their use is governed by a data-use agreement with the Observatório de Saúde Cardiovascular (Instituto Nacional de Cardiologia) and Brazil's General Data Protection Law (LGPD); aggregated, de-identified hospitalization coefficients and case-fatality ratios are reported in the associated manuscript.本仓库包含支撑巴西孕产妇呼吸道合胞病毒（respiratory syncytial virus, RSV）疫苗接种成本效益分析的决策分析模型文件与分析结果，共涵盖三类分析场景：汇总行政数据场景、基于外部临床试验发病率基准（MATISSE）的场景，以及由关联住院与出生记录衍生的高捕获率场景。本仓库包含以下内容：(1) 适用于各场景的Amua决策树模型文件（后缀为.amua），其中包含确定性敏感性分析与概率敏感性分析的配置规范；(2) 各场景下单因素确定性敏感性分析（deterministic sensitivity analysis, DSA）与概率敏感性分析（probabilistic sensitivity analysis, PSA，含10000次蒙特卡洛迭代）的原始与汇总结果。个体层面的关联微观数据未纳入本仓库，因其使用需遵循与巴西心血管健康观测站（国家心脏病学研究所）签署的数据使用协议，以及巴西通用数据保护法（LGPD）的相关规定；汇总后的去标识化住院系数与病例死亡率已在关联学术论文中予以披露。