Regulating intestinal microecologic health agent combination chemotherapy in the treatment of advanced colorectal cancer research

Interventions: General nutrition intervention group:Guidance of diet+Oral nutritional supplements;Regulating intestinal microecologic health agent group:Guidance of diet+Oral nutritional supplements+Regulating intestinal microecologic health agent;Guide the diet group:Guidance of diet Primary outcome(s): stool test;blood routine examination;Biochemical routine;tumor marker;Chest computed tomography;The abdominal computed tomography Study Design: Randomized parallel controlled trial