A comparison of strategies for mixing WGBS libraries
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA486075
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资源简介：
The nucleotide composition of sequencing library for whole-genome bisulfite sequencing (WGBS) is extremely biased. This causes inaccurate base calling on Illumina's sequencers. To overcome this, we conceived a strategy that mixes two libraries of the reciprocal polarities for sequencing direction. We compared this strategy with a conventional one that mixes WGBS library with a library of normal nucleotide composition called PhiX.
创建时间：
2018-08-15
