The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 I

ChEBI2014-12-17 更新2026-07-21 收录

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基因转录调控

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The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 I

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2014-12-17

Nanoscale Dynamics of Enhancer-Promoter Interactions during Exit from Pluripotency

染色质空间构象

基因转录调控

While compelling genetic evidence supports the role of enhancers in regulating promoter activity even over large genomic distances, it remains unclear to what extent physical proximity to promoters is

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E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase ɛ B-subunit gene POLE2

基因转录调控

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The B-subunits of replicative DNA polymerases from Archaea to humans belong to the same protein family, suggesting that they share a common fundamental function. We report here the gene structure for

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RNA-seq: STAT1 and STAT3 transcription factors sense and interpret changes in inflammation through engagement of specific enhancers

转录因子调控

炎症信号通路

RNA-seq: STAT1 and STAT3 transcription factors sense and interpret changes in inflammation through engagement of specific enhancers

ChEBI2022-04-04 更新10

FTH1P3, a Novel H-Ferritin Pseudogene Transcriptionally Active, Is Ubiquitously Expressed and Regulated during Cell Differentiation

基因转录调控

细胞分化机制

Ferritin, the major iron storage protein, performs its essential functions in the cytoplasm, nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light (L) type composes

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A minimal DNA sequence within the ARF promoter represses p16INK4A expression via long-range chromatin interaction [Cut&Run ChiP-seq]. A minimal DNA sequence within the ARF promoter represses p16INK4A expression via long-range chromatin interaction [Cut&Run ChiP-seq]

基因转录调控

染色质相互作用

Loss of function of CDKN2A/B, also known as INK4/ARF [encoding for p16INK4A, p15INK4B, and p14ARF (mouse p19Arf)]), confers susceptibility to cancers, whereas its up-regulation during organismal aging

NIAID Data Ecosystem40

The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 I

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