Joint-Structural Biology Group (JSBG) BAG proposal for ID29 beamline
收藏ESRF Portal2028-01-01 更新2026-04-23 收录
下载链接：
https://doi.esrf.fr/10.15151/ESRF-ES-2115013372
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资源简介：
The aim of the JSBG BAG proposal for ID29 beamline is to develop new methods for time-resolved serial crystallography experiments at 4th generation source and to study time dependent structural conformation of biological macromolecules that are studies at the ESRF-EMBL-GR Joint Structural Biology Group. Method developments include the study of radiation damage at high flux densities and with partially polychromatic beam (1% and 0.3%), the implementation and development of various sample delivery methods - mixing in capillary, microfluidics, tape-drive and fixed targets. This further includes development of GPU-based indexing algorithm, data reduction software, and develop new data collection strategies for pump-probe SSX experiments integrating nanosecond laser. Biological systems include the study of photoactivatable proteins, enzymatic systems through mixing experiments and multi-temperature jump experiments to study protein dynamics.
提供机构：
i3S-IBMC, Macromolecular Structure, Rua Alfredo Allen 208, Porto, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular, i3S, Rua Alfredo Allen 208, 4200-135 Porto, Portugal; EMBL Grenoble, 71 avenue des Martyrs, CS 90181, 38042 Grenoble Cedex 09, France; ESRF, 71 avenue des Martyrs, CS 40220, 38043 Grenoble Cedex 9, France
创建时间：
2028-01-01
