Descriptive summary of six HNSCC datasets.

*71 of these HNSCC samples contained survival information and were included for prognosis validation (Fig. 6) and all samples were included for diagnosis validation (Fig. 5).A description of the TNM stage, P53 status, HPV status, smoking status and alcohol intake status is reported in Table S8A–8C.P: paired samples: each patient contributed two samples (one HNSCC tumor sample and one control non tumor oral tissue).