MRI data for "Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the spreading, aggregation, and toxicity of α-synuclein in vivo"

Repository for magnetic resonance imaging data from the project titled "Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the spreading, aggregation, and toxicity of α-synuclein in vivo" Contains the pre-processed ex vivo T1-weighted images (Bruker 7T; 70 micron isotropic voxel resolution) for WT mice, M83 homozygous, and M83 homozygous mice with one copy of the TPR transgene. Full subject list can be viewed with the prado_MRI_M83dTPR_subjectlist_final.csv file. Whole brain region segmentations are available for these mice. These labels were generated using the MAGeT-Brain segementation pipleine (https://github.com/CobraLab/MAGeTbrain) and using a modified/merged version of the Allen brain atlas. The full list of regions included can be found in the file named Allen_brain_mapping_final.csv. See readme.txt file for more information本数据集仓库收录了题为《应激诱导型磷酸蛋白1（HOP/STI1/STIP1）调控α-突触核蛋白在体内的扩散、聚集与毒性》的研究项目的磁共振成像（magnetic resonance imaging, MRI）数据。包含野生型（WT）小鼠、M83纯合子小鼠以及携带单份TPR转基因拷贝的M83纯合子小鼠的预处理离体T1加权成像数据（布鲁克7T扫描仪；各向同性体素分辨率为70微米）。完整受试者列表可通过prado_MRI_M83dTPR_subjectlist_final.csv文件查阅。上述所有小鼠的全脑区域分割结果均已提供，这些分割标签通过MAGeT-Brain分割流水线（https://github.com/CobraLab/MAGeTbrain）以及经修改合并的艾伦脑图谱（Allen brain atlas）版本生成。所涵盖的完整脑区列表可在Allen_brain_mapping_final.csv文件中获取，更多详细信息请参阅readme.txt文件。