Phase Separation of Ligand-Activated Enhancers Licenses Cooperative Chromosomal Enhancer Assembly

NIAID Data Ecosystem2026-03-12 收录

增强子相互作用

染色体增强子组装

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE99544 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2021-07-25

Cis-regulation between Irf8 enhancers during cDC1 development (ATAC-Seq)

树突状细胞发育

增强子相互作用

Type 1 classical dendritic cells (cDC1s) development requires the transcription factor IRF8, and IRF8 mutations cause severe combined immunodeficiency, including disseminated bacille Calmette-GuÃ©rin

NIAID Data Ecosystem80

Antagonistic role of Hnf4a and FoxO1 metabolic networks through enhancer interactions in beta-cell function [ChIP-seq]. Antagonistic role of Hnf4a and FoxO1 metabolic networks through enhancer interactions in beta-cell function [ChIP-seq]

细胞转录调控

增强子相互作用

To identify transcription factors in Foxo1's network with H3K27ac ChIPseq performed in WT and beta cell-specific Foxo1 knockout beta cells. Overall design: We performed H3K27ac ChIPseq in FAC-sorted b

NIAID Data Ecosystem30

Phase Separation of Ligand-Activated Enhancers Licenses Cooperative Chromosomal Enhancer Assembly [GRO-seq_RAW]

增强子相互作用

GRO-seq转录分析

Acutely activated enhancer in response to cell signaling regulate transcrption by assembling phase separated ribonucleoprotein complex composed of transcription factors with disordered domains and RNA

NIAID Data Ecosystem20

Phase Separation of Ligand-Activated Enhancers Licenses Cooperative Chromosomal Enhancer Assembly [ChIP-seq]

增强子相互作用

ChIP-seq分析

Signal stimulation activate enhancers by acutey assembling phase separated ribonucleoprotein complexes on transcriptional enhancers ChIP-Seq experiments were designed to understand the genomic distrib

NIAID Data Ecosystem50

Characterization of tissue-specific BMAL1 cistromes reveals new roles for enhancer-enhancer interactions in regulating rhythmic transcription [ChIA-PET]

转录调控

增强子相互作用

The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of thousands of genes and enable biological functions to anticipate the daily environ

NIAID Data Ecosystem20

Phase Separation of Ligand-Activated Enhancers Licenses Cooperative Chromosomal Enhancer Assembly

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