该数据集包含了人类RASH蛋白质单点突变及其对应的突变效应分数，这些分数来自于深度突变扫描实验。蛋白质的格式为氨基酸序列。数据集分为训练集、验证集和测试集，分别包含2479、338和317个样本。标签表示基于深度突变扫描实验的每个蛋白质的突变效应分数，范围从负无穷大到正无穷大，其中0代表野生型的值，数值越大表示适应性越高。

Hugging Face2025-05-13 更新70

Alanine-Scanning mutagenesis of MreB

蛋白质功能位点

丙氨酸扫描技术

MreB is a protein involved in cell shape. We made a mutant library to determine important residues. Some mutants completely lost cell shape and were sequenced for possible suppressor mutations.

NIAID Data Ecosystem20

Table S1 - Identification of Functional Amino Acid Residues Involved in Polyamine and Agmatine Transport by Human Organic Cation Transporter 2

蛋白质功能位点

定点突变

List of oligonucleotide primers used for mutagenesis. (PDF)

NIAID Data Ecosystem70

Additional file 5: of A statistical framework for analyzing deep mutational scanning data

深度突变扫描

药物靶点筛选

Variants with higher scores than wild-type in the presence of oseltamivir. (XLSX 11 kb)

Figshare2017-08-08 更新30