Additional file 2: of Naked mole-rat transcriptome signatures of socially suppressed sexual maturation and links of reproduction to aging

Table S1. Age at death for NMRs and GPs. Table S2. Number of analyzed biological replicates per group. Table S3. Reason for exclusion of samples from further analysis. Table S4. Number of uniquely aligned RNA-seq reads. Table S5. Mean pairwise Pearson correlation coefficients between biological replicates in (A) naked mole-rat and (B) guinea pig. Table S22. Proportion of mitochondrial transcriptonal output. Table S25. Enrichment of age-related genes (Digital Ageing Atlas) in status-related DEGs. Only tissues having at least 50 DEGs were tested for enrichment. Table S27. Fisher’s exact test for overlap between DAA and upper quintile of status-related expression differences. Table S10, S12, S15–17, S19–21, S28, S29. Functional gene set enrichments analyses—see Overview tab for detailed description. Table S7–9, S11, S13, S14, S18, S23, S24, S26. Differentially expressed genes—see Overview tab for detailed description. (XLSX 313 kb)

表S1 裸鼹鼠（Naked Mole-Rat, NMR）与豚鼠（Guinea Pig, GP）的死亡年龄
表S2 各组分析所用生物学重复样本数量
表S3 样本被排除于后续分析的原因
表S4 唯一比对至参考序列的RNA测序（RNA-seq）读段数
表S5 （A）裸鼹鼠、（B）豚鼠的生物学重复样本间的平均成对Pearson相关系数
表S22 线粒体转录产物占比
表S25 衰老相关基因（数字衰老图谱，Digital Ageing Atlas, DAA）在状态相关差异表达基因（Differentially Expressed Genes, DEG）中的富集分析。仅纳入至少包含50个差异表达基因的组织进行富集检验
表S27 针对数字衰老图谱基因与状态相关表达差异上五分位基因集之间重叠情况的Fisher精确检验
表S10、S12、S15至S17、S19至S21、S28、S29：功能基因集富集分析——详细说明请参见概述标签页
表S7至S9、S11、S13、S14、S18、S23、S24、S26：差异表达基因列表——详细说明请参见概述标签页
（XLSX格式，文件大小313千字节）