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Transcriptome profiling of osteoblasts treated with uMSC-derived exosomes

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To investigate the function and affected pathways of uMSC-derived exosomes on ossification, we used human and rat osteoblast cell line hFOB1.19 and ROS1728 treated with either exosomes or exosome-free supernatent (which is the supernatent of exosome pelleting after ultracentrifugation) and a non-treated group as negative control. We take advantages of high through-put sequencing technology to fully reveal the transcriptome changes of the treated cells.

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