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Sequencing of EcoSeq libraries

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP008753
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The Enzymatically Cleaved and Optimal Sequencing (EcoSeq) method was able to count somatic mutations in a single DNA molecule with high efficiency (low sequencing cost), high accuracy (distinction of single-stranded premutagenic lesions and sequence errors), and high sensitivity (detection limit of 3Ã?10^-8 bp). EcoSeq has the potential to reveal accumulation of somatic mutations and exposure to environmental factors in any DNA samples, and will contribute to cancer risk estimation.
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2022-07-15
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