OPPERA I prospective cohort for first onset of TMJD. Homo sapiens

The OPPERA project investigates effects of genetic, physiological, psychological and clinical factors on risk of developing painful temporomandibular disorder. The prospective cohort study evaluated factors at enrollment that predicted subsequent risk of developing first-onset temporomandibular disorder (TMD). Between May 2006 and November 2008, 3,263 study participants with no significant history of TMD were enrolled at four U.S. study sites. They were followed for a median period of 2.8 years, during which time 260 of them developed examiner-verified, first-onset TMD.