Raw Data - Cardiotox and Safety Screen from De Korte et al - Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening

Raw data transcript data from 3 screens performed of cMTs with either voltage or calcium investigating inotropic compounds as part of a safety and cardiotoxicity screening. Data consists of baseline recordings and 30min post compound addition recordings, and attached plate plan. The attached data is the raw traces that were used to calculate differences that are found in published paper and also attached open access application - https://davis-lab-cardiotox.streamlit.app/ This data is part of De Korte et al: Industrialization of three-dimensional hiPSC-cardiac microtissues for high-throughput cardiac safety and drug discovery screening (in preparation)本数据集为针对心脏微组织（cardiac microtissues, cMTs）开展的3轮筛选的原始转录数据，该筛选以电压或钙信号为检测指标，用于探究正性肌力化合物的作用，属于安全性与心脏毒性筛查的研究内容之一。数据集包含基线记录、化合物添加后30分钟的记录，以及附带的培养板布局图。附带的数据为用于计算已发表论文中所报道差异的原始波形轨迹，同时附带了开源在线应用程序，链接为：https://davis-lab-cardiotox.streamlit.app/ 本数据集隶属于De Korte等人的研究成果：《用于高通量心脏安全性与药物发现筛选的三维诱导多能干细胞（human induced pluripotent stem cell, hiPSC）心脏微组织工业化构建》（待发表）