Results of mutation analysis for the 13 assays for 43 NSCLC subjects.
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For each subject the origin of the cytological material and the mutational status for each of the 13 assays are indicated. Only one subject (40) shows a discordance on a single assay (boxed cell), which may be explained from the commonly observed genetic divergence of metastasis from its primary tumor.‘P’, primary tumor; ‘M’, metastasis; ‘√’, concordance of wildtype result from mutation analysis between histology and cytology; ‘mut’, concordant samples with a somatic mutation; ‘−/+’, discordant result, mutation in the cytological and wildtype in the histological material; ‘−/?’, wildtype signal in the histology with discordancy in the cytological material because of low signal; ‘?/−’, Low signal in the histological material and wildtype signal in the cytology.



