Comparison of liver mRNA expression between Control AA and Low AA diet fed mice

The goal of the experiment was to examine hepatic gene expression differences induced by a low protein high carbohydrate diet. We used chemically defined diets based on naturally defined diets first published and completely described in Fontana et al., 2016, Cell Reports. 9 week old C57BL/6J mice were fed either Control (TD.140711) or Low AA (TD.140712) diets for 4 months and then sacrificed after an overnight ~16 hour fast. 8 total samples were examined - 4 from Control AA and 4 from Low AA diet fed mice.