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Comparison between mouse hepatocytes derived from wt and YAP transgenic livers

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE89284
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Primary isolated hepatocytes derived from wildtype mice are compared with hepatocytes isolated from YAP(S127A) transgenic mice (Tschaharganeh at al., 2013 Gastroenterology, PMID 23419361). YAP induction was done for 8 weeks and livers showed hyperplasia without signs of malignant transformation. Three independent wildtype mice are compared with three independent YAP transgenics.
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2017-10-20
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