Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110
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Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110 Descriptor: 4-[(1R)-1-[1-(4-chlorophenyl)-1,2,3-triazol-4-yl]ethoxy]-1-oxidanyl-quinoline, ACETIC ACID, FORMIC ACID, ... Authors: Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Gu, M, Zhang, M, Mandapati, K, Gollapalli, D.R, Gorla, S.K, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2014-04-10 Release date: 2014-07-09 Last modified: 2026-03-25 Method: X-RAY DIFFRACTION (2.885 Å) Cite: A novel cofactor-binding mode in bacterial IMP dehydrogenases explains inhibitor selectivity. J.Biol.Chem., 290, 2015
产气荚膜梭菌（Clostridium perfringens）肌苷5'-单磷酸脱氢酶（Inosine 5'-monophosphate Dehydrogenase）与肌苷单磷酸（IMP）及A110复合物的晶体结构
配体描述：4-[(1R)-1-[1-(4-氯苯基)-1,2,3-三唑-4-基]乙氧基]-1-羟基喹啉、乙酸、甲酸……
作者：Maltseva N、Kim Y、Makowska-Grzyska M、Mulligan R、Gu M、Zhang M、Mandapati K、Gollapalli DR、Gorla SK、Hedstrom L、Anderson WF、Joachimiak A；依托单位：感染性疾病结构基因组学中心（Center for Structural Genomics of Infectious Diseases, CSGID）
提交日期：2014-04-10
发布日期：2014-07-09
最后更新日期：2026-03-25
检测方法：X射线衍射（X-RAY DIFFRACTION，2.885埃）
引用文献：《细菌肌苷单磷酸脱氢酶中一种新型辅因子结合模式阐释抑制剂选择性》，J. Biol. Chem., 290, 2015
创建时间：
2014-04-10
