Per-site per-gene estimates of selection posterior densities
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'site_hpds.csv' summarizes selection coefficients obtained by renaissance counting.<br>It contains 12 columns: * 'subject': Subject for the analyzed sample ('A', 'B', or 'C').<br>* 'sample': A sample identifier.<br>* 'gene': The IGHV gene and allele analyzed.<br>* 'variable': One of:<br>- 'dN' - the nonsynonymous substitution rate.<br>- 'dS' - the synonymous substitution rate.<br>- 'dNdS' - the selection coefficient, omega.<br>* 'subset': Subset of sequences represented by the row. One of:<br>- 'out-of-frame': out of frame sequences only.<br>- 'productive': in frame sequences without stop-codons identified.<br>- 'productive/out-of-frame': productive rates normalized by out-of-frame rates. See manuscript for details.<br>* 'site': The codon site within the V gene.<br>* 'imgt_site': The codon site within the V gene, using IMGT unique numbering.<br>* 'median': Median value<br>* 'hpdLower': Lower bound of the 95% HPD interval.<br>* 'hpdUpper': Upper bound of the 95% HPD interval.<br>* 'coverage': Number of sequences analyzed covering this position.<br>* 'oof_coverage': Number of out-of-frame sequences covering this position. The selection coefficients presented in the manuscript are the subset of rows for which:<br>* 'oof_coverage > 100'<br>* 'subset == "productive/out-of-frame"'<br>* 'variable == "dNdS"'
提供机构:
figshare
创建时间:
2015-05-04



