Gut microbiota de novo Parkinson's disease

The gut microbial communities of treatment-naïve de novo Parkinson's disease subjects were analyzed in two cohorts. One comparing the fecal microbiota of 136 Parkinson's disease subjects to 85 healthy controls and another comparing 56 Parkinson's disease subjects to 87 healthy controls. Gut microbiota of fecal samples were analyzed with amplicon sequencing of the V4 variable region of the 16S rRNA gene on Illumina MiSeq. NOTE: (1) The initial submission contained several duplicate files. Please only use the corrected database, which was uploaded on February 28th 2023. (2) Each file contains the combined results of four sequencing runs. If preferable for downstream processing (eg. DADA2 sample inference), please use the run number and/or flowcell ID in the sequence indentifier lines to differentiate between runs.