Data and analysis for: "Persistent Spatial Clustering and Predictors of Pediatric La Crosse Virus Neuroinvasive Disease Risk in Eastern Tennessee and Western North Carolina, 2003–2020"

This is the initial release of the data and code corresponding to the manuscript submitted to PLoS Neglected Tropical Diseases. Please refer to the README.md file for a description of the contents of this repository and how to use them. The README file can be opened with a text editor, or viewed directly in the GitHub repository. The data and code are provided within a project directory with a reproducible R package library for ease and accuracy of reproducibility. Ethics Approval This study was approved by the University of Tennessee, Knoxville Institutional Review Board (UTK IRB-22-07079-XP) and the Tennessee Department of Health Institutional Review Board (TDH IRB 2021-0314). Data provided here is de-identified and aggregated (both temporally and spatially) to protect the privacy of individuals included in the study, in concordance with IRB and Data Use Agreements.本数据集与代码为投稿至《公共科学图书馆·被忽视的热带病》(PLoS Neglected Tropical Diseases)的研究论文的首次公开发布版本。请参阅README.md文件，了解本代码仓库的内容说明与使用方法。README文件可通过文本编辑器打开，或直接在GitHub代码仓库中查看。本数据集与代码封装于项目目录中，并附带可复现的R包(R package)依赖库，以保障研究复现的便捷性与准确性。 伦理批准 本研究已通过田纳西大学诺克斯维尔分校机构审查委员会(UTK IRB-22-07079-XP)和田纳西州卫生部机构审查委员会(TDH IRB 2021-0314)的伦理审查。根据机构审查委员会要求与数据使用协议，本仓库提供的数据已完成去标识化处理，并进行了时空维度的聚合，以保护研究涉及个体的隐私。