Parameter estimates, dN/dS, values of log-Likelihood (l), positive selection sites, and Likelihood Ratio Tests (LRT) in the G-gene analysis of RSV-A viruses circulating in Ontario, Canada between November 2010 and February 2011.
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See Methods for explanation of terms used in parameter estimates column.Neutral models (M1a, and M7) were compared with their respective alternative (selection) models (M2a and M8), which allow ω>1. Model comparison can be calculated using 2Δl = 2 (l1−l0)), where l1 = LRT of alternative model; and l0 = LRT of null model. Proportion of positively selected sites and their corresponding ω-values in M2a and M8 models are in bold. The significant P values indicated that all analyses find very strong evidence for the selection model.aPositively selected sites using Bayes Empirical Bayes analysis [28]. Posterior probability of positively selected sites of M2a model: 50% to 74% (213, 218, 237, 285); 85% to 94% (233, 274); and >95% (232, 250, 251, 253, 265, 266, 273). Posterior probability of positively selected sites of M8 model: 50% to 74% (213, 218, 234, 249, 260, 277, 286); 75% to 84% (237, 285); 85% to 94% (233); and >95% (232, 250, 251, 253, 265, 266, 273, 274, 290).
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2015-12-02



