Spatial mapping of genomic data to tissue context in a high-throughput and high-resolution manner has been challenging due to technical limitations. Here, we describe a novel approach, phenotype-based
Heterogeneity of ROR2 was observed in the tumor tissues form patient-derived xenograft (PDX) model of SCLC, in which the cells with high ROR2 expression (ROR2high cell) and those without ROR2 expressi
All source data and materials of cellular function and molecular biology assays to demonstrate FAK/SFK axis-mediated the tyrosine phosphorylation of ACLY and ALDOA to induce the downstream reprogram,
Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t