Lu-177 Phantom scans at 8 Belgian hospitals using 13 clinical SPECT/CT systems

Data of a uniform cylindrical and a NEMA phantom with hot spheres and a cold background that were scanned at 8 Belgian hospitals using 13 different SPECT/CT systems. The phantoms were prepared and scanned at UZ Leuven, before being shipped for measurement at 7 other Belgian hospitals over the course of two weeks. Acquisitions and reconstructions were performed using the existing clinical protocols at each site, but also using standardized settings. The resulting dataset therefore reflects the current clinical situation of Lu-177 imaging, as well as the potential of harmonizing acquisition and reconstruction protocols. The non-standardized images highlight the variability in clinical images resulting from variable site-specific protocols. The standardized images show consistency between systems of the same type, but differences between different system type remain large. The measurement of the activity in both phantoms was traceable to primary standards. For more details on phantom preparation scanner types and scanner protocols, see "Multicenter Comparison of Radionuclide Calibrators and SPECT/CT Protocols for Quantitative 177Lu Imaging in Clinical Practice"本数据集涵盖均匀圆柱形体模及搭载热球体与冷背景的NEMA体模（NEMA phantom）的扫描数据，上述体模由13台不同的SPECT/CT系统（SPECT/CT system）在8家比利时医院完成扫描。 该批体模先在鲁汶大学医院（UZ Leuven）完成制备与初始扫描，随后被运往其余7家比利时医院，在两周内完成后续测量。各站点均采用本地现有临床协议完成数据采集与图像重建，同时也使用了标准化参数设置。因此，所得数据集既反映了镥-177（Lu-177）显像当前的临床实践现状，也体现了统一采集与重建协议的可行性与潜力。非标准化图像直观展现了因站点专属协议差异导致的临床图像变异性；标准化图像则呈现出同类型系统间的一致性，但不同类型系统之间仍存在显著差异。两种体模的活度测量值均可追溯至一级标准。 如需了解体模制备、扫描仪类型及扫描仪协议的更多细节，请参阅"Multicenter Comparison of Radionuclide Calibrators and SPECT/CT Protocols for Quantitative 177Lu Imaging in Clinical Practice"一文。