Transcriptomic alterations of stromal cells during ageing. Transcriptomic alterations of stromal cells during ageing

The hematopoietic microenviroment plays a pivotal role in erythropoiesis. Here we compare the transcriptome profiles of the bone marrow niche. in young and aged mice Overall design: Examine the gene expression profile of different stromal populations in the bone marrow for young (8-12 weeks) and aged (24-25 months) mice by bulk RNA-seq (100 cells)