The structure of trans-3-chloroacrylic acid dehalogenase, covalently inactivated by the mechanism-based inhibitor 3-bromopropiolate at 2.3 Angstrom resolution

The structure of trans-3-chloroacrylic acid dehalogenase, covalently inactivated by the mechanism-based inhibitor 3-bromopropiolate at 2.3 Angstrom resolution Descriptor: MALONIC ACID, alpha-subunit of trans-3-chloroacrylic acid dehalogenase, beta-subunit of trans-3-chloroacrylic acid dehalogenase Authors: de Jong, R.M, Brugman, W, Poelarends, G.J, Whitman, C.P, Dijkstra, B.W. Deposit date: 2004-01-05 Release date: 2004-02-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily J.Biol.Chem., 279, 2004本数据集包含经基于机制的抑制剂（mechanism-based inhibitor）3-溴丙炔酸（3-bromopropiolate）共价灭活的反式-3-氯丙烯酸脱卤酶（trans-3-chloroacrylic acid dehalogenase）的三维结构，解析分辨率为2.3埃。 描述项：丙二酸（MALONIC ACID）、反式-3-氯丙烯酸脱卤酶α亚基、反式-3-氯丙烯酸脱卤酶β亚基 作者：de Jong, R.M.、Brugman, W.、Poelarends, G.J.、Whitman, C.P.、Dijkstra, B.W. 入库日期：2004-01-05 发布日期：2004-02-24 最后修改日期：2023-08-23 实验方法：X射线衍射（X-RAY DIFFRACTION），解析分辨率2.3埃 引用文献：《反式-3-氯丙烯酸脱卤酶的X射线结构揭示了互变异构酶超家族（tautomerase superfamily）中的新型水合机制》，J.Biol.Chem., 279, 2004