Enteric neuronal GPR41-DHX9 signaling senses microbial metabolites to mediate the crosstalk between serotonergic neurons and intestinal stem cells [RNA-seq]. Enteric neuronal GPR41-DHX9 signaling senses microbial metabolites to mediate the crosstalk between serotonergic neurons and intestinal stem cells [RNA-seq]

We show that enteric neuronal Dhx9 is important for proper bowel motility and nutrient absorption which are required for intestine development. Overall design: To systematically explore the molecular events underlying the intestine developmental defects, we performed bulk RNA sequencing analysis on the total duodenum.