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Identification of RNAs that are physically and functionally associated with RNase P

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10514
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Numerous RNAs copurify with RNase P and are affected by temperture sensitive mutations in conserved residues with the essential RNA and protein subunits. Specifically, RNase P physically interacts with ribosomal protein mRNAS and the intron-encoded box C/D snoRNAs. Keywords: RNA copurification, temperature sensitive mutants ORF and intergenic regions were analyzed in order to determine which RNAs were affected in RNase P strains.
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2012-03-19
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