Commenting round on the draft corrected Test Guideline 456 on the H295R Steroidogenesis Assay
收藏Organisation for Economic Co-operation and Development2026-04-11 收录
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https://www.oecd.org/en/events/public-consultations/2024/12/commenting-round-on-the-draft-corrected-test-guideline-456-on-the-h295r-steroidogenesis-assay.html
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In 2022, Test Guideline 456: H295R Steroidogenesis Assay was revised and a new data interpretation procedure (DIP) adopted. This new DIP introduced a new (additional) criteria to conclude to a positive result (induction or inhibition), i.e. result > 1.5-fold induction or inhibition threshold from the solvent control. It recently appeared that this...
