Comparison of parameter values for IGF1-IGF1R binding.
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We estimated rate constants (defined as indicated in Fig 2) by fitting to IGF1-IGF1R binding data [44] using the BioNetFit software package [61]. We calculated the 95% confidence interval for each parameter using a bootstrapping procedure (see Material and Methods). The parameter a'2 was taken to be given by Eq 1 and the values of the other rate constants.
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2019-01-30
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