BIOGRID CURATED DATA FOR CLB1 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for CLB1 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB1 has a paralog, CLB2, that arose from the whole genome duplication

蛋白质-蛋白质、遗传和化学相互作用数据集，针对酿酒酵母（Saccharomyces cerevisiae (S288c)）中的CLB1基因，由BioGRID（https://thebiogrid.org）编纂；定义：B型细胞周期蛋白，参与细胞周期进程；激活Cdc28p以促进G2到M期的转换；在G2和M期积累，随后通过破坏盒结构域被泛素化，进而由蛋白酶体介导降解；CLB1拥有一个同源基因CLB2，该基因起源于全基因组复制。