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Leptinotarsa decemlineata Epigenomics

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP541819
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We report the epigenetic landscape of Leptinotarsa decemlineata, a beetle species that has lost DNMT3 but retained CpG methylation. We combined whole body (mixed sex) RNA-seq (embryo, adult), enzymatic methyl-seq (embryo, adult) and CUT&Tag (embryo) to study CpG methylation and patterns of H3K36me3 and H3K27ac histone modifications on a genome-wide scale. Our study provides new insights into the evolutionary flexibility of epigenetic modification systems that urge caution when generalizing across species.
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2025-05-19
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