Cdh13 null mice isolated islets RNAseq

The pancreas islets RNA expressions were compared between WT (exon2 floxed) mice and Cdh13 KO (exon2 deleted) mice. The islets were isolated from the mice at 8wks old, 14wks old under normal chow diet, and 14wks old under HFD conditions. Baseline at 8wks old. WT (n=3) and Cdh13 KO (n=3). 14wks old under normal chow. WT (n=3) and Cdh13 KO (n=3). 14wks old under HFD conditions, WT (n=3) and Cdh13 KO (n=3).HFD was started at 8wks old.本数据集对比了野生型（exon2 floxed）小鼠与Cdh13基因外显子2敲除（Cdh13 KO）小鼠的胰岛RNA表达谱。实验采样分为以下三组： 1. 基线组：正常饲料喂养下，于8周龄时从小鼠体内分离胰岛； 2. 正常饲料喂养组：于14周龄时分离胰岛； 3. 高脂饮食（High-Fat Diet, HFD）组：于8周龄开始给予高脂饮食，于14周龄时分离胰岛。 所有分组的样本量均为：野生型小鼠3只（n=3），Cdh13 KO小鼠3只（n=3）。