Comparison of national implementation of the 2013 ACC/AHA guidelines and treating all persons with high-dose statins strategies with other population based strategies—Comparing CHD events prevented, costs saved, and QALYs gained for each strategy compared to status quo.

*Costs and QALYs of weight reduction based on lifetime model of intense dietary, exercise, and lifestyle modification which assumed that over time participants would gain back a significant component of their initial weight loss.
#Based on average blood pressure reduction from all medication interventions in ALLHAT which included chlorthalidone, amlodipine, and Lisinopril for hypertensive patients with at least one CHD risk factor. The blood pressure reduction achieved was a decrease in SBP of 12mm Hg and in DBP of 9mm Hg. At studies end 66% of patients achieved a blood pressure of goal of < 140/90
ALLHAT = The antihypertensive and lipid lowering treatment to prevent heart attack trial, BMI = body mass index, CHD = coronary heart disease, DBP = diastolic blood pressure, QALY = quality adjusted life year, SBP = systolic blood pressure
Comparison of national implementation of the 2013 ACC/AHA guidelines and treating all persons with high-dose statins strategies with other population based strategies—Comparing CHD events prevented, costs saved, and QALYs gained for each strategy compared to status quo.