Telmisartan PKs of 48 health males with different genotypes.

Data were shown as mean±SD;
*P<0.05; **P<0.01.
PKs, pharmacokinetics; ORM1, orosomucoid 1; ABCC2, ATP-binding cassette, sub-family C, member 2; ABCG2, ATP-binding cassette, sub-family G, member 2; ABCB1, ATP-binding cassette, sub-family B, member 1; SLCO1B3, solute carrier organic anion transporter family, member 1B3; SNP, single nucleotide polymorphisms; AUC(0–48) the area under the plasma concentration-time curve (AUC) from 0 to 48 h; AUC(0–∞), AUC from 0 to ∞; Cmax, the peak concentration in plasma; CL/F, clearance; T1/2, elimination half-life; Tmax, the time to Cmax.