Putative Cdk5-dependent phosphorylation sites downregulated in Cdk5^−/− brains.

In bold type phosphorylated sites previously described in other mouse brain phosphoproteomic studies but lacking an assigned protein kinase responsible for such a phosphorylation. a: phosphorylated by Cdk5, b: phosphorylated by Cdk1; c: phosphorylated by Cdk2. PSSM scores determined as Borquez et al, 2013. NetphosK scores calculated using public protein prediction tool. Asterisks (*) indicated Cdk5 is the best kinase for a given site. Candidates validated in the present study are presented in italics type.