Transcriptional landscape of facet joint osteoarthritis insights into facet cartilage degeneration. Homo sapiens

Facet joint osteoarthritis is common lumbar osteoarthritis characterized by facet joint cartilage degeneration. Till now, the cellular and molecular mechanisms of facet joint osteoarthritis remain largely undetermined. With confirmation of the quality and reliability of the RNA-seq data, we will proceed to identify the expression changes of coding and noncoding RNAs in facet joint osteoarthritis and thus will expand our understanding of the molecular changes underlying facet joint osteoarthritis.