Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5

Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 Descriptor: 1,2-ETHANEDIOL, 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, ACETATE ION, ... Authors: Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. Deposit date: 2024-04-25 Release date: 2024-05-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Potency-Enhanced Peptidomimetic VHL Ligands with Improved Oral Bioavailability. J.Med.Chem., 67, 2024VHL、ElonginB、ElonginC与化合物5形成的复合物的晶体结构。描述符：1,2-乙二醇、3-(吡啶-4-基)-2,4-二氢茚并[1,2-c]吡唑、乙酸根离子等。作者：Murray, J.M.、Wu, H.、Fuhrmann, J.、Fairbrother, W.J.、DiPasquale, A.。提交日期：2024-04-25。发布日期：2024-05-29。末次修改日期：2024-10-16。测试方法：X射线衍射（X-RAY DIFFRACTION），分辨率为2.47埃。引用文献：《药效增强型拟肽VHL配体及其优化的口服生物利用度》，《药物化学杂志》（J.Med.Chem.），第67卷，2024年。