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Investigate the anti-tumor mechanisms of But4ManNAc and butyrate in two breast cancer cell lines

ChEBI2011-06-14 更新2026-07-21 收录

乳腺癌药物机制

肿瘤药理学

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29922 数据链接链接失效反馈

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资源简介：

Investigate the anti-tumor mechanisms of But4ManNAc and butyrate in two breast cancer cell lines

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创建时间：

2011-06-14

天然化合物抗肿瘤

肿瘤药理学

Cancer can develop due to abnormal cell proliferation in any body’s cells, so there are over a hundred different types of cancer, each with its distinct behavior and response to treatment. Therefore,

NIAID Data Ecosystem60

Inhibition of A549 cell viability by trypacidin.

肿瘤药理学

毒性评估

A549 cells were exposed for 1 h and 2 h with 10 µM and 50 µM trypacidin, then the medium containing trypacidin was replaced by fresh medium and cell viability was measured 24 h later using MTT assay.

NIAID Data Ecosystem50

Anti-proliferative effect of Cinobufagin on acute myeloid leukemia cells with repression of c-Myc pathway associated genes (ChIP-Seq)

肿瘤药理学

功能基因组学

To analyse the effect of Cinobufagin to human acute myeloid leukemia cell lines, HL60 and Kasumi-1. Overall design: 1) HL60 cells were treated with 100nM Cinobufagin for 24 hours 2) Kasumi-1 cells wer

NIAID Data Ecosystem20

Main mechanism of action of cisplatin, gemcitabine, vinorelbine and docetaxel.

药物作用机制

肿瘤药理学

Main mechanism of action of cisplatin, gemcitabine, vinorelbine and docetaxel.

NIAID Data Ecosystem60

DataSheet1_Novel iron chelator SK4 demonstrates cytotoxicity in a range of tumour derived cell lines.docx

肿瘤药理学

抗肿瘤药物开发

Iron is an essential micronutrient due to its involvement in many cellular processes including DNA replication and OXPHOS. Tumors overexpress iron metabolism linked proteins which allow for iron accum

NIAID Data Ecosystem40

Investigate the anti-tumor mechanisms of But4ManNAc and butyrate in two breast cancer cell lines

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