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Interaction with Cholangiocytes and Neutrophils

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NIAID Data Ecosystem2026-03-12 收录
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Alcoholic hepatitis (AH) is a life-threatening disease with limited treatment options. The presence of cholestasis worsens prognosis but the responsible mechanism is unknown. AH results in infiltration of polymorphonuclear neutrophils (PMNs) in the liver, and cholestasis often reflects bile duct pathology, so we investigated whether and how PMNs interact with cholangiocytes in AH. RNA was isolated from NHC with non-coculture condition and after coculture condition.

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2021-03-02
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