Data from: Clinical spectrum and risk factors associated with asymptomatic erosive esophagitis as determined by Los Angeles classification: a cross-sectional study

Background: Gastro esophageal reflux disease (GERD) is a chronic and recurrent disease, and it varies in regions. However, to date, there are no reports available on clinical features and the risk factors for the asymptomatic reflux esophagitis in Nepalese adults. Methods: Data were gathered from 142 erosive patients who had undergone endoscopy at Bir Hospital, Kathmandu. Los Angeles classification was used to grade the severity of the disease. Patients were interviewed to find out the presence of various reflux symptoms. Results: Based on the Los Angeles classification, the severity of the disease assessed was; grade A 31.8% (31/142), grade B 39.4 % (56/142), grade C 33.8% (48/142), and grade D 4.9% (7/142). One hundred and twenty six (88.7%) subjects had reflux symptoms. Prevalence of asymptomatic esophagits was 16(11.3%). Age was independently linked to asymptomatic esophagitis (P<0.05), and the odd of being asymptomatic appeared lower in younger adults (P<0.05; OR: 0.118; CI: 0.014-.994). Conclusion: A low prevalence of asymptomatic reflux esophagits (RE) was seen. Most subjects experienced mild to moderate RE. Age remained an independent factors associated with reflux esophagitis, and the odd of being asymptomatic was lower in younger age.

背景：胃食管反流病（Gastro esophageal reflux disease, GERD）是一种慢性复发性疾病，存在地域差异。截至目前，尚无关于尼泊尔成人无症状反流性食管炎的临床特征及危险因素的相关报道。
方法：研究数据收集自尼泊尔加德满都比尔医院接受内镜检查的142例糜烂性患者。采用洛杉矶分类法（Los Angeles classification）对疾病严重程度进行分级。通过访谈获取患者各类反流症状的相关信息。
结果：依据洛杉矶分类法，本次评估的疾病严重程度分布为：A级31.8%（31/142）、B级39.4%（56/142）、C级33.8%（48/142）、D级4.9%（7/142）。共计126例（88.7%）受试者存在反流症状。无症状食管炎的患病率为16例（11.3%）。年龄与无症状食管炎呈独立相关（P<0.05），年轻成人出现无症状状态的比值比（Odds Ratio, OR）更低（P<0.05；置信区间（Confidence Interval, CI）：0.014~0.994）。
结论：本研究中无症状反流性食管炎（Reflux Esophagitis, RE）的患病率较低。多数受试者表现为轻至中度反流性食管炎。年龄仍是与反流性食管炎相关的独立危险因素，年轻群体出现无症状反流性食管炎的概率更低。