Eigen software for functional genomic annotations

Eigen is a spectral approach integrating functional genomic annotations for coding and noncoding variants. The training and testing datasets used in the Eigen paper and the R scripts implementing model training and calculation of Eigen scores are available for download. Information about the paper and the precomputed genome-wide Eigen scores is available at http://www.funlda.com/toolkit.

Eigen是一种整合编码与非编码变异功能基因组注释的谱方法（spectral approach）。Eigen相关论文中使用的训练与测试数据集，以及用于实现模型训练和Eigen得分计算的R脚本，均可下载获取。有关该论文的详细信息以及预计算的全基因组Eigen得分，可通过http://www.funlda.com/toolkit获取。