Dataset related to article "Cold versus hot EMR for large duodenal adenomas "
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This record contains raw data related to article “Cold versus hot EMR for large duodenal adenomas" Conventional endoscopic mucosal resection using electrocoagulation (hot EMR) for large (>20 mm), sporadic non-ampullary duodenal adenomas is associated with a high complication rate. Based on favourable colonic experience with cold EMR/without electrocautery, we performed a retrospective analysis comparing 33 patients treated this way to 101 patients who had hot EMR for their duodenal adenomas. Data were collected from four tertiary centres in two time periods. No serious adverse events (SAEs) occurred in the cold group, there were 17 intraprocedural SAEs (16.8%) and 26 postprocedural SAEs (25.7%) in the hot EMR group. Procedure time was significantly lower for cold EMR (49±25.1 min vs 96.9±56 min, p<0.01). Recurrence seen at first follow-up endoscopy was comparable in both groups (cold EMR: 4/33; 12.1% versus hot EMR: 21/101; 20.8%). This data suggests that cold EMR is a safe and feasible option for the removal of large non-ampullary duodenal adenomas
本数据集包含与论文《大型十二指肠腺瘤的冷内镜黏膜切除术vs热内镜黏膜切除术》相关的原始数据。针对直径>20mm的散发性非壶腹部十二指肠腺瘤,采用电凝法的传统内镜黏膜切除术(Endoscopic Mucosal Resection,EMR,热EMR)并发症发生率较高。鉴于冷EMR(无需电凝)在结肠领域的应用效果良好,本研究开展了一项回顾性分析,对比33例接受冷EMR治疗的十二指肠腺瘤患者与101例接受热EMR治疗的同类患者。研究数据来源于两个时间段内的四家三级医疗中心。冷EMR组未发生任何严重不良事件(Serious Adverse Events,SAEs);热EMR组则出现17例术中严重不良事件(占比16.8%)及26例术后严重不良事件(占比25.7%)。冷EMR组的手术时长显著更短(49±25.1分钟 vs 96.9±56分钟,p<0.01)。首次随访内镜检查显示的复发率在两组间无显著差异(冷EMR组:4/33,占比12.1%;热EMR组:21/101,占比20.8%)。本研究数据表明,冷EMR是切除大型非壶腹部十二指肠腺瘤的安全且可行的治疗方案。



