George Richenberg PhD thesis - Supplementary table 6.10: Summary statistics for sfFDR-identified novel genome-wide significant (FP<5x10-8), independent lead variants associated with overall (inc), overall (exc), DNMT3A-, TET2- and ASXL1-mutant CH compared with the 15 blood cell traits in BCX2
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Summary statistics for novel, genome-wide significant (FP<5×10⁻⁸), independent lead variants associated with CH risk identified using the sfFDR method in individuals of European ancestry (25,657 cases and 342,869 controls). These variants were compared against association results for 15 blood cell traits measured in 562,132 European ancestry individuals from the Blood Cell Consortium (Phase 2) (PMID: 32888493).
本数据集包含通过sfFDR方法在欧洲血统人群(25657名病例与342869名对照个体)中鉴定得到的、与CH风险相关的新发、全基因组显著(FP<5×10⁻⁸)的独立先导变异的汇总统计量。将上述变异与来自血细胞联盟(Blood Cell Consortium,第二阶段)、在562132名欧洲血统个体中测得的15种血细胞性状的关联分析结果进行了比对,相关研究的文献编号为PMID: 32888493。
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2025-08-08



