Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

ChEBI2012-08-16 更新2026-07-21 收录

胰岛细胞药物反应

糖尿病肾病治疗

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Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

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2012-08-16

Efficacy and potential pharmacological mechanism of Astragalus-Salvia miltiorrhiza combination in diabetic nephropathy: integrating meta-analysis, network pharmacology, molecular docking, and experimental validation

糖尿病肾病治疗

药物机制研究

Diabetic nephropathy (DN) is a diabetes mellitus (DM)-induced complication that poses high morbidity and mortality risks. The Astragalus and Salvia miltiorrhiza couplet medicines (AS) ar

DataCite Commons2026-05-21 更新100

DataSheet8_Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis.ZIP

糖尿病肾病治疗

细胞焦亡机制

Background: Fucoidan (FPS) has been widely used to treat renal fibrosis (RF) in patients with diabetic kidney disease (DKD); however, the precise therapeutic mechanisms remain unclear. Recently, resea

NIAID Data Ecosystem30

Sacubitril/Valsartan helps against diabetic kidney disease and modulates gut microbiota combined with metabolome in mice. Mus musculus

糖尿病肾病治疗

肠道微生物与代谢

Diabetic kidney disease (DKD), a serious microvascular complication of diabetes, had limted treatment options. Sacubitril/Valsartan (Sac/Val) is reported to improve kidney function. Gut microbiota dys

NIAID Data Ecosystem20

Effect of Hemodialysis on Plasma Glucose Profile and Plasma Level of Liraglutide in Patients with Type 2 Diabetes Mellitus and End-Stage Renal Disease: A Pilot Study

糖尿病肾病治疗

临床病理学

The effect of hemodialysis on the plasma glucose profile and liraglutide level after liraglutide injection was investigated in patients with diabetes and end-stage renal disease (ESRD). Either 0.6 mg

NIAID Data Ecosystem50

DataSheet4_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP

糖尿病肾病治疗

细胞损伤机制

Objective: To observe the therapeutic effect of Yi-Shen-Hua-Shi (YSHS) granule in podocyte damage and diabetic nephropathy (DN) proteinuria and to explore the corresponding mechanism. Methods: The db/

NIAID Data Ecosystem20

Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

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