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Formal Synthesis of (±)-Tetrodotoxin via the Oxidative Amidation of a Phenol: On the Structure of the Sato Lactone

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https://figshare.com/articles/dataset/Formal_Synthesis_of_Tetrodotoxin_via_the_Oxidative_Amidation_of_a_Phenol_On_the_Structure_of_the_Sato_Lactone/2207296
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资源简介:
A formal total synthesis of (±)-tetrodotoxin that relies on the bimolecular oxidative amidation of a phenol is described, and a structural correction of the Sato lactone, an important tetrodotoxin intermediate, is provided. This work lays the foundation for an ultimate enantioselective synthesis.
创建时间:
2016-02-15
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