Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment. Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment

We performed single nucleus RNA-seq on rat fetal lungs from: control (normal), hypoplastic (injury), and hypoplastic+ amniotic fluid stem cell extracellular vesicles treated (injury+treatment). Overall design: Single nucleus RNA-seq on rat fetal lungs at E21.5. Conditions: 1) control (normal), 2) hypoplastic (injury), and 3) hypoplastic+ amniotic fluid stem cell extracellular vesicles treated (injury+treatment)