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Transcriptome analysis of CNS and splenic FOXP3+ Tregs vs. exFOXP3 T cells during EAE

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NIAID Data Ecosystem2026-05-02 收录
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EAE was induced in female FOXP3 fate mapping mice. At peak of disease, immune cells were isolated from brain and spinal cord (pooled as CNS) and spleen. Next, FOXP3+ and exFOXP3 T cells were FACS-sorted based on RFP and GFP expression. FOXP3+ Tregs are sorted as GFP+RFP+ and exFOXP3 T cells as GFP-RFP+.

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2024-06-12
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