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Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

ChEBI2010-07-08 更新2026-07-21 收录

母细胞瘤发病机制

神经发育转录调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-19684 数据链接链接失效反馈

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Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

应用场景：

创建时间：

2010-07-08

神经发育转录调控

ChIP-Seq峰分析

In this file we provide the raw sequencing counts and number of peaks for each ChIP-Seq experiment with individual antibodies used in this study. (XLSX 7 kb)

NIAID Data Ecosystem90

Single-cell RNA-seq Reveals a Developmental Hierarchy and Oncogenic Networks for Initiation of Medulloblastoma

单细胞肿瘤学

母细胞瘤发病机制

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

RXR mediated neurogenesis (ChIP-Seq)

神经发育转录调控

RXR受体

A growing number of pieces of evidence suggest the importance of Retinoid X Receptor (RXR)-mediated pathways in neurogenesis and the dysregulation of this signaling in neurodegenerative disorders, suc

NIAID Data Ecosystem30

FOXP2 regulates differential transcriptional programs in human subplate

神经发育转录调控

FOXO基因功能

Mammalian brains are highly conserved at both the neuroanatomical and gene expression levels. However, the subplate is a neocortical subregion distinguished by a markedly different developmental traje

NIAID Data Ecosystem60

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression [human sWGS]. IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression [human sWGS]

母细胞瘤发病机制

基因治疗靶点

Chromosome 17q gain is an independent prognostic marker in neuroblastoma, harboring several potential oncogenes including IGF2BP1 and BIRC5. IGF2BP1 was shown to be upregulated in unfavorable neurobla

NIAID Data Ecosystem50

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

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