Crystal structure of human BAZ2A bromodomain in complex with a diacetylated histone 4 peptide (H4K16acK20ac)

Protein Data Bank Japan2024-11-20 更新2026-03-21 收录

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Crystal structure of human BAZ2A bromodomain in complex with a diacetylated histone 4 peptide (H4K16acK20ac) Descriptor: 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2A, histone H4 peptide with sequence Gly-Ala-Lys(ac)-Arg-His-Arg-Lys(ac)-Val-Leu Authors: Tallant, C, Nunez-Alonso, G, Picaud, S, Filippakopoulos, P, Krojer, T, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2014-05-08 Release date: 2014-05-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Molecular basis of histone tail recognition by human TIP5 PHD finger and bromodomain of the chromatin remodeling complex NoRC. Structure, 23, 2015

人源BAZ2A溴结构域与双乙酰化组蛋白H4肽（H4K16acK20ac）复合物的晶体结构描述：1,2-乙二醇（1,2-ETHANEDIOL）、锌指结构域相邻溴结构域蛋白2A、序列为Gly-Ala-Lys(ac)-Arg-His-Arg-Lys(ac)-Val-Leu的组蛋白H4肽作者：Tallant, C、Nunez-Alonso, G、Picaud, S、Filippakopoulos, P、Krojer, T、Williams, E、von Delft, F、Arrowsmith, C.H、Edwards, A.M、Bountra, C、Knapp, S、结构基因组学联盟（Structural Genomics Consortium, SGC）存放日期：2014-05-08 发布日期：2014-05-21 最后修改日期：2024-11-20 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.65 Å）引用文献：《人类TIP5 PHD指结构域与染色质重塑复合物NoRC的溴结构域识别组蛋白尾部的分子基础》，《Structure》，23卷，2015年

创建时间：

2014-05-08